Cysteine protease inhibitor PD 151746, Purity ≥98%

Synonym: 179461-52-0; Cysteine protease inhibitor; PD-151746; PD151746

CAS Number: 179461-52-0
Compound CID: 5353866

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

PD 151746, soluble in DMSO and ethanol and insoluble in water, obstructs cysteine proteases, enzymes implicated in numerous diseases due to their role in protein degradation. It targets μ-calpain and m-calpain.

Molecular Weight

237.25

Molecular Formula

C₁₁H₈FNO₂S

Targets

μ-Calpain: 260 nM; m-calpain: 5.33 μM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 40 mg/mL (168.6 mM); Water: Insoluble; Ethanol: 40 mg/mL (168.6 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

PD 151746 has an inhibitory effect on cysteine proteases and helps explore treatment options for diseases such as cancer.