Properties
Description
Abiraterone acetate, soluble in DMSO and ethanol and insoluble in water, is an effective cell metabolism inhibitor, that has the ability to prevent the pathway of metabolism by inhibiting cytochrome P450. It targets the CYP17 (cell-free assay).
Molecular Formula
C26H33NO2
Targets
CYP17 (Cell-free assay): 72 nM
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO: insoluble; Water: insoluble; Ethanol: 27 mg/mL; In vivo: 5% DMSO + 95% Corn oil, 28 mg/mL
Stability
In its lyophilized form, the chemical remains stable for 36 months.
Quality Level
Research grade
Applications
Abiraterone acetate is a metabolism inhibitor that can be studied extensively for its potential therapeutic applications in the treatment of prostate cancer.
Storage
Store at -20ºC, and keep desiccated.