Properties
Description
Avasimibe, soluble in DMSO and ethanol and insoluble in water, is an effective cell metabolism inhibitor, that has the ability to prevent the pathway of metabolism by inhibiting cytochrome P450. It targets the ACAT, CYP1A2, CYP2C19, and CYP2C9.
Molecular Formula
C29H43NO4S
Targets
ACAT: 3.3 μM; CYP1A2: 13.9 μM; CYP2C19: 26.5 μM; CYP2C9: 2.9 μM
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO: 96 mg/mL (191.34 mM); Water: insoluble; Ethanol: 8 mg/mL (15.94 mM); In vivo: 2% DMSO + corn oil, 4 mg/mL
Stability
In its lyophilized form, the chemical remains stable for 36 months.
Quality Level
Research grade
Applications
Avasimibe is a metabolism inhibitor that can be studied extensively for its potential therapeutic applications in the treatment of conditions like atherosclerosis.
Storage
Store at -20ºC, and keep desiccated.
