Properties
Description
Deferasirox, soluble in DMSO and ethanol and insoluble in water, is an effective cell metabolism inhibitor, that has the ability to prevent the pathway of metabolism by inhibiting cytochrome P450.
Molecular Formula
C21H15N3O4
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO: 64 mg/mL (171.42 mM); Water: insoluble; Ethanol: 2 mg/mL; In vivo: 5% DMSO + 40% PEG 300 + 5% Tween 80 + 50% H2O, 3.5 mg/mL
Stability
In its lyophilized form, the chemical remains stable for 36 months.
Quality Level
Research grade
Applications
Deferasirox is a metabolism inhibitor that can be studied extensively for its potential therapeutic applications in the treatment of chronic iron overload due to conditions such as thalassemia or sideroblastic anemia, often resulting from repeated blood transfusions.
Storage
Store at -20ºC, and keep desiccated.
