Cytochrome P450 inhibitor, Deferasirox, Purity ≥98%

Synonym: 201530-41-8; ICL-670; ICL-670A; CGP-72670; 4-[3,5-Bis(2-hydroxyphenyl)-1,2,4-triazol-1-yl]benzoic acid

MDL: MFCD09751362
CAS Number: 201530-41-8
Compound CID: 214348

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

MSDS

Properties

Description

Deferasirox, soluble in DMSO and ethanol and insoluble in water, is an effective cell metabolism inhibitor, that has the ability to prevent the pathway of metabolism by inhibiting cytochrome P450.

Molecular Weight

373.36

Molecular Formula

C₂₁H₁₅N₃O₄

Form

Lyophilized powder

Purity

Titer

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects

Solubility

In vitro: DMSO: 64 mg/mL (171.42 mM); Water: insoluble; Ethanol: 2 mg/mL; In vivo: 5% DMSO + 40% PEG 300 + 5% Tween 80 + 50% H₂O, 3.5 mg/mL

Applications

Deferasirox is a metabolism inhibitor that can be studied extensively for its potential therapeutic applications in the treatment of chronic iron overload due to conditions such as thalassemia or sideroblastic anemia, often resulting from repeated blood transfusions.