Cytochrome P450 inhibitor, Itraconazole, Purity ≥98%

Synonym: 84625-61-6; Oriconazole; Itraconazol; Itrizole; Itrizole (TN); Sporanox (TN); ITCZ; 2-Butan-2-yl-4-[4-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-1,2,4-triazol-3-one

MDL: MFCD00941396
CAS Number: 84625-61-6
Compound CID: 55283

Product Size

100 mg; 250 mg; 500 mg; 1000 mg

Price

Datasheet

MSDS

Properties

Description

Itraconazole, soluble in warmed DMSO and insoluble in water and ethanol, is an effective cell metabolism inhibitor, that has the ability to prevent the pathway of metabolism by inhibiting cytochrome P450.

Molecular Weight

705.65

Molecular Formula

C₃₅H₃₈Cl₂N₈O₄

Form

Lyophilized powder

Purity

Titer

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects

Solubility

In vitro: DMSO (warmed): 7 mg/mL (9.91 mM); Water: insoluble; Ethanol: insoluble; In vivo: 5% DMSO + 40% PEG 300 + 10% Tween 80 + 45% ddH₂O, 1.66 mg/mL

Applications

Itraconazole is a metabolism inhibitor that can be studied extensively for its potential therapeutic applications in the treatment of fungal infections, including aspergillosis, blastomycosis, histoplasmosis, and onychomycosis.