Properties
Description
Itraconazole, soluble in warmed DMSO and insoluble in water and ethanol, is an effective cell metabolism inhibitor, that has the ability to prevent the pathway of metabolism by inhibiting cytochrome P450.
Molecular Formula
C35H38Cl2N8O4
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO (warmed): 7 mg/mL (9.91 mM); Water: insoluble; Ethanol: insoluble; In vivo: 5% DMSO + 40% PEG 300 + 10% Tween 80 + 45% ddH2O, 1.66 mg/mL
Stability
In its lyophilized form, the chemical remains stable for 36 months.
Quality Level
Research grade
Applications
Itraconazole is a metabolism inhibitor that can be studied extensively for its potential therapeutic applications in the treatment of fungal infections, including aspergillosis, blastomycosis, histoplasmosis, and onychomycosis.
Storage
Store at -20ºC, and keep desiccated.
