Cytochrome P450 inhibitor, PF 4981517, Purity ≥98%

Synonym: 1390637-82-7; PF4981517; PF-4981517; 1-Methyl-3-[1-methyl-5-(4-methylphenyl)pyrazol-4-yl]-4-[(3S)-3-piperidin-1-ylpyrrolidin-1-yl]pyrazolo[3,4-d]pyrimidine

MDL: MFCD22417344
CAS Number: 1390637-82-7
Compound CID: 71315139

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

PF 4981517, soluble in DMSO and insoluble in water and ethanol, is an effective cell metabolism inhibitor, that has the ability to prevent the pathway of metabolism by inhibiting cytochrome P450. It targets the CYP3A4.

Molecular Weight

456.59

Molecular Formula

C₂₆H₃₂N₈

Targets

CYP3A4: 30 nM

Form

Lyophilized powder

Purity

≥98%

Titer

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects

Solubility

In vitro: DMSO: 85 mg/mL (186.16 mM); Water: insoluble; Ethanol: insoluble

Stability

In its lyophilized form, the chemical remains stable for 36 months.

Quality Level

Research grade

Applications

PF 4981517 is a metabolism inhibitor that can be studied extensively for its potential therapeutic applications in the treatment of cancer and other diseases.

Storage

Store at -20ºC, and keep desiccated.