Cytochrome P450 inhibitor, Posaconazole, Purity ≥98%

Synonym: 171228-49-2; Noxafil; Posaconazole SP; SCH56592; Schering 56592; 4-[4-[4-[4-[[(3R,5R)-5-(2,4-Difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)oxolan-3-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-2-[(2S,3S)-2-hydroxypentan-3-yl]-1,2,4-triazol-3-one

MDL: MFCD00941162
CAS Number: 171228-49-2
Compound CID: 468595

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Posaconazole, soluble in DMSO and insoluble in water and ethanol, is an effective cell metabolism inhibitor, that has the ability to prevent the pathway of metabolism by inhibiting cytochrome P450.

Molecular Weight

700.8

Molecular Formula

C₃₇H₄₂F₂N₈O₄

Form

Lyophilized powder

Purity

≥98%

Titer

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects

Solubility

In vitro: DMSO: 90 mg/mL (128.42 mM); Water: insoluble; Ethanol: insoluble; In vivo: 1% DMSO + 30% polyethylene glycol + 1% Tween 80, 28 mg/mL

Stability

In its lyophilized form, the chemical remains stable for 36 months.

Quality Level

Research grade

Applications

Posaconazole is a metabolism inhibitor that can be studied extensively for its potential therapeutic applications in the treatment of a variety of fungal infections.

Storage

Store at -20ºC, and keep desiccated.