Properties
Description
TH-302, soluble in DMSO, warmed water and ethanol, is an effective cell metabolism inhibitor, that has the ability to prevent the pathway of metabolism by inhibiting cytochrome P450.
Molecular Formula
C9H16Br2N5O4P
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO: 80 mg/mL (178.15 mM); Water (warmed): 9 mg/mL (20.03 mM); Ethanol: 80 mg/mL (178.15 mM); In vivo: 30% propylene glycol, 5% Tween 80, 65% D5W, 28 mg/mL
Stability
In its lyophilized form, the chemical remains stable for 36 months.
Quality Level
Research grade
Applications
TH-302 is a metabolism inhibitor that can be used for its ability to release cytotoxic agents in low-oxygen environments typical of solid tumors.
Storage
Store at -20ºC, and keep desiccated.
