Properties
Description
Dehydrocostus lactone (DHE), a natural sesquiterpene lactone, inhibits IKKβ activity, IκBα phosphorylation and degradation, coactivators p300 recruitments and p50/p65 NF-κB nuclear translocation.
Molecular Formula
C15H18O2
Source
Vladimiria souliei(Franch. )Ling
Purity
>98%, determined by HPLC.
Solubility
It is soluble in ethyl acetate, acetone, DMSO and other solvents, but insoluble in water.
Identity
Confirmed by NMR and MS.
Applications
Dehydrocostus lactone can be used for anti-inflammatory, anti-ulcer, immunomodulatory and anti-tumor property experiments, etc.