Dehydrogenase inhibitor, Brequinar, Purity ≥98%

Synonym: 96187-53-0; 6-Fluoro-2-(2'-fluoro-[1,1'-biphenyl]-4-yl)-3-methylquinoline-4-carboxylic acid; Brequinarum; Biphenquinate; 6-Fluoro-2-(2'-fluorobiphenyl-4-yl)-3-methylquinoline-4-carboxylic acid; 6-Fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methylquinoline-4-carboxylic acid; 6-Fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methylquinoline-4-carboxylic acid; Dehydrogenase inhibitor

MDL: MFCD00866437
CAS Number: 96187-53-0
Compound CID: 57030

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Brequinar, soluble in DMSO and insoluble in water and ethanol, is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting dehydrogenases. The molecular weight of the compound is 375.37, and its molecular formula is C₂₂H₁₃F₂NO₂.

Molecular Weight

375.37

Molecular Formula

C₂₂H₁₃F₂NO₂

Form

Lyophilized powder

Purity

≥98%

Impurities

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.

Solubility

In vitro: DMSO: 36 mg/mL (95.9 mM); Water: insoluble; Ethanol: insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

Brequinar can be studied extensively for its potential therapeutic applications in the treatment of various cancers including lymphoma and leukemia.