Dehydrogenase inhibitor, NCT-501, Purity ≥98%

Synonym: 1802088-50-1; NCT501; NCT 501; 8-[[4-(Cyclopropanecarbonyl)piperazin-1-yl]methyl]-1,3-dimethyl-7-(3-methylbutyl)purine-2,6-dione; Dehydrogenase inhibitor

MDL: MFCD29472261
CAS Number: 1802088-50-1
Compound CID: 92044412

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

NCT-501, soluble in DMSO and ethanol and insoluble in water, is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting dehydrogenases. The molecular weight of the compound is 416.52, and its molecular formula is C₂₁H₃₂N₆O₃. It targets the ALDH1A1.

Molecular Weight

416.52

Molecular Formula

C₂₁H₃₂N₆O₃

Targets

ALDH1A1

Form

Lyophilized powder

Purity

≥98%

Impurities

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.

Solubility

In vitro: DMSO (warmed): 30 mg/mL (72.02 mM); Water: insoluble; Ethanol: 24 mg/mL (57.62 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

NCT-501 can be studied extensively for its potential therapeutic applications in the treatment of cancers associated with this mutation, such as gliomas and AML, by restoring normal cellular metabolism.