Properties
Description
Deoxyribonuclease II from porcine spleen is an endonuclease that plays a key role in setting up phosphodiester bonds, preferentially adjacent to pyrimidine nucleotides, yielding polynucleotides with a free hydroxyl group at the 3' position.
Molecular Weight
38.0 kDa
Unit Definition
One unit causes an increase in absorbance at 260 nm of 0.001 per minute at 25°C, pH 4.6 using highly polymerized DNA as substrate.
Applications
Deoxyribonuclease II from porcine spleen is useful for DNA removal in bioprocessing applications.
