DHFR inhibitor, Aminopterin, Purity ≥98%

Synonym: 54-62-6; 4-Aminopteroic acid; 4-Amino-PGA; APGA; Aminopteridine; Aminotrexate; Aminopterine; 4-Aminopteroylglutamic acid; (2S)-2-[[4-[(2,4-Diaminopteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid; DHFR inhibitor

MDL: MFCD00036692
CAS Number: 54-62-6
Compound CID: 169371

Product Size

50 mg; 100 mg; 200 mg; 500 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Aminopterin is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting DHFR. The molecular weight of the compound is 440.4, and its molecular formula is C₁₉H₂₀N₈O₅.

Molecular Weight

440.4

Molecular Formula

C₁₉H₂₀N₈O₅

Form

Lyophilized powder

Purity

≥98%

Impurities

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.

Identity

Confirmed by NMR/HPLC/MS.

Applications

Aminopterin plays a key role in inhibiting DHFR, which is crucial for DNA synthesis, thereby impeding cancer cell proliferation.