Dihydrostreptomycin Sulfate Analysis Service

Dihydrostreptomycin Sulfate Analysis Service

Precision in Every Step: Unveiling the Potential of Dihydrostreptomycin Sulfate Analysis with Excellence

Dihydrostreptomycin sulfate is an aminoglycoside antibiotic with strong bactericidal activity, low toxicity, broad indications, and good clinical efficacy. In the medical field, dihydrostreptomycin sulfate is often used as dihydrostreptomycin sulfate boluses. At CD BioGlyco, we have extensive experience in Pharmaceutical and Biological Analysis and provide comprehensive dihydrostreptomycin sulfate analysis services to our clients.

Comprehensive Dihydrostreptomycin Sulfate Analysis Service at CD BioGlyco

  • Properties
    Dihydrostreptomycin sulfate molecular formula is (C21H41N7O12)2·3H2SO4, molecular weight is 1461.42 g/mol. It is a kind of white to light yellow crystalline powder, and easy to dissolve in water.
  • Identification
    The sample to be tested is dissolved in water, to which naphthol solution and sodium hydroxide solution are added in turn. If a red color appears in the solution, the sample is dihydrostreptomycin sulfate.
  • pH
    The dihydrostreptomycin sulfate (boluses) is dissolved completely in water and then will be tested for pH. Dihydrostreptomycin sulfate should have a pH between 4.5-7.0. Alternatively, the pH of the dihydrostreptomycin sulfate boluses should be between 3.0 and 7.0.
  • Loss on drying
    The sample to be tested is weighed and placed in a capillary-stoppered bottle and then dried. Loss of weight of dihydrostreptomycin sulfate should not exceed 5.0%. Loss of weight of dihydrostreptomycin sulfate boluses should not exceed 14.0%.
  • Content test
    We will dissolve the samples in water and then the absorbance at specific wavelengths is measured by an ultraviolet-visible (UV) spectrophotometer, followed by a graph of absorbance versus concentration of the samples. The content of dihydrostreptomycin sulfate in the samples is calculated from the graph.

Fig.1 Dihydrostreptomycin sulfate analysis services. (CD BioGlyco)Fig.1 Dihydrostreptomycin sulfate analysis services. (CD BioGlyco)

Publication Data

Technology: Liquid chromatography (LC), UV detection

Journal: Journal of Pharmaceutical and Biomedical Analysis

IF: 3.4

Published: 2000

Results: The authors purified and analyzed dihydrostreptomycin sulfate using a reversed-phase silica gel LC column with a base-inactivated column as stationary phase and UV detection at 205 nm. This method allowed the separation of 11 fractions including streptane, dihydrostreptomycin B, streptomycin, dihydrostreptomycin, and dehydrostreptomycin, and the total time for analysis was less than 1h.

Applications

  • Dihydrostreptomycin sulfate belongs to the class of aminoglycoside antibiotics, and its analysis helps to fully explore the biological functions of aminoglycoside antibiotics.
  • Dihydrostreptomycin sulfate is indicated for infections caused by a wide range of bacteria and is used in veterinary clinical trials. We offer dihydrostreptomycin sulfate analysis which can be used in veterinary research in the field of antimicrobials.

Advantages

  • Our pharmaceutical analysis team consists of multidisciplinary technical talents to provide high-level Pharmaceutical Analysis services and solve complex technical and application problems.
  • We provide custom drug analysis services according to the needs of our clients, helping them to overcome their research challenges in a targeted manner.
  • We have advanced analysis techniques to accurately analyze and validate most drug structures and biological activities.

CD BioGlyco is a world-class specialized biotechnology company with extensive experience in the field of pharmaceutical analysis, and we offer a full range of pharmaceutical analysis to our clients all over the world. If you would like to know more about our services, please feel free to contact us.

Reference

  1. Adams, E.; et al. Liquid chromatographic analysis of dihydrostreptomycin sulfate. Journal of Pharmaceutical and Biomedical Analysis. 2000, 21(4): 715-722.
This service is for Research Use Only, not intended for any clinical use.

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