DNA alkylator inhibitor, Thiotepa, Purity ≥98%

Cat. No.: X24-08-YM146

DNA alkylator inhibitor, Thiotepa, Purity ≥98%

Synonym: 52-24-4; AI324916; NSC6396; Girostan; TioTEF; Tris(aziridin-1-yl)-sulfanylidene-λ5-phosphane

  • MDL: MFCD00145452
  • CAS Number: 52-24-4
  • Compound CID: 5453
Product Size
500 mg; 1 g; 2 g; 5 g
Price
Datasheet
MSDS
Properties
Description
Thiotepa, soluble in DMSO, warmed water and ethanol, is an effective DNA damage inhibitor, that has the ability to prevent the pathway of DNA damage by inhibiting DNA alkylator.
Molecular Weight
189.22
Molecular Formula
C6H12N3PS
Form
Lyophilized powder
Purity
≥98%
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO: 88 mg/mL (465.06 mM); Water (warmed): 88 mg/mL (465.06 mM); Ethanol: 88 mg/mL (465.06 mM)
Stability
In its lyophilized form, the chemical remains stable for 36 months.
Quality Level
Research grade
Applications
Thiotepa is a DNA damage inhibitor that can be studied extensively for its potential therapeutic applications in the treatment of breast cancer, ovarian cancer, and bladder cancer, by cross-linking DNA and interfering with cancer cell replication.
Storage
Store at -20ºC, and keep desiccated.
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