DNA-PK inhibitor NU7026, Purity ≥98%

Synonym: 154447-35-5; NU 7026; NU-7026; DNA-PK inhibitor

CAS Number: 154447-35-5
Compound CID: 9860529

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

NU7026, soluble in DMSO and insoluble in ethanol and water, impairs the non-homologous end joining (NHEJ) pathway of DNA repair, thereby sensitizing cancer cells to treatments that induce DNA double-strand breaks. It targets ATM, ATR, DNA-PK, and PI3K.

Molecular Weight

281.31

Molecular Formula

C₁₇H₁₅NO₃

Targets

ATM: >100 μM; ATR: >100 μM; DNA-PK: 0.23 μM; PI3K: 13 μM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 1 mg/mL (3.55 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

NU7026 can be used to investigate its role as a DNA-PK inhibitor and its impact on cell cycle regulation and cancer cell survival.