Properties
Description
Dacarbazine, soluble in warmed DMSO, warmed water and warmed ethanol, is an effective DNA damage inhibitor, that has the ability to prevent the pathway of DNA damage by inhibiting DNA-RNA synthesis.
Molecular Formula
C6H10N6O
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO (warmed): 12 mg/mL (65.86 mM); Water (warmed): 2 mg/mL (10.97 mM); Ethanol (warmed): 1 mg/mL (5.48 mM); In vivo: 0.5% CMC Na, 28 mg/mL
Stability
In its lyophilized form, the chemical remains stable for 36 months.
Quality Level
Research grade
Applications
Dacarbazine is a DNA damage inhibitor that plays a key role in adding alkyl groups to DNA, leading to cross-linking and preventing DNA replication, thereby inducing cancer cell death.
Storage
Store at -20ºC, and keep desiccated.
