DNA-RNA synthesis inhibitor, Lomustine, Purity ≥98%

Synonym: 13010-47-4; CeeNU; 1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea

MDL: MFCD00012392
CAS Number: 13010-47-4
Compound CID: 3950

Product Size

50 mg; 100 mg; 250 mg; 500 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Lomustine, soluble in DMSO and insoluble in water and ethanol, is an effective DNA damage inhibitor, that has the ability to prevent the pathway of DNA damage by inhibiting DNA-RNA synthesis.

Molecular Weight

233.69

Molecular Formula

C₉H₁₆ClN₃O₂

Form

Lyophilized powder

Purity

≥98%

Titer

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects

Solubility

In vitro: DMSO: 40 mg/mL (171.16 mM); Water: insoluble; Ethanol: insoluble; In vivo: 30% propylene glycol, 5% Tween 80, 65% D5W, pH 4, 9 mg/mL

Applications

Lomustine is a DNA damage inhibitor that can be studied extensively for its potential therapeutic applications in the treatment of brain tumors and Hodgkin lymphoma.