DNMT inhibitor RG108, Purity ≥98%

Synonym: 48208-26-0; RG 108; RG-108; DNA methyltransferase inhibitor

CAS Number: 48208-26-0
Compound CID: 702558

Product Size

25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

RG108, soluble in DMSO and ethanol and insoluble in water, blocks the addition of methyl groups to DNA by methyltransferases, impacting gene expression and genome stability. It targets DNA methyltransferase.

Molecular Weight

334.33

Molecular Formula

C₁₉H₁₄N₂O₄

Targets

DNA methyltransferase: 115 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 62 mg/mL (185.44 mM); Water: Insoluble; Ethanol: 62 mg/mL (185.44 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

RG108 can be used to inhibit DNA methyltransferases in cancer and epigenetic research.