Properties
Description
Dolasetron Mesylate, soluble in DMSO and water, and insoluble in ethanol, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets 5-HT3 receptor.
Molecular Formula
C20H24N2O6S
Solubility
DMSO: 81 mg/mL (192.64 mM); Water: 27 mg/mL (64.21 mM); Ethanol: insoluble
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Dolasetron mesylate can be studied for its effect on blocking serotonin receptors in the brain, specifically the 5-HT3 receptors, which are involved in the initiation of vomiting reflexes.
Storage
Store at -20°C, and keep desiccated.
