Properties
Description
Domperidone, soluble in DMSO and ethanol and insoluble in water, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets dopamine D2 receptor.
Molecular Formula
C22H24ClN5O2
Targets
Dopamine D2 receptor
Solubility
DMSO: 47 mg/mL (110.34 mM); Water: insoluble; Ethanol: 1 mg/mL (2.34 mM)
Applications
Domperidone can be used for its effect on increasing prolactin levels, which in turn enhances milk production.