Donitriptan

Synonym: 170912-52-4; 1-(((3-(2-Aminoethyl)indol-5-yl)oxy)acetyl)-4-(p-cyanophenyl)piperazine

CAS Number: 170912-52-4
Compound CID: 197706

Product Size

1 mg; 5 mg; 10 mg; 50 mg

Price

Datasheet

MSDS

Properties

Description

Donitriptan inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets 5-HT1B receptor, and 5-HT1D receptor.

Molecular Weight

403.48

Molecular Formula

C₂₃H₂₅N₅O₂

Targets

5-HT1B receptor: 9.4 (pKi); 5-HT1D receptor: 9.3 (pKi)

Form

Lyophilized powder

Purity

Applications

Donitriptan can be used to research and develop therapeutic strategies for certain diseases that involve excessive activation of GPCR-G protein signaling pathways.