Donitriptan

Synonym: 170912-52-4; 1-(((3-(2-Aminoethyl)indol-5-yl)oxy)acetyl)-4-(p-cyanophenyl)piperazine

CAS Number: 170912-52-4
Compound CID: 197706

Product Size

1 mg; 5 mg; 10 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Donitriptan inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets 5-HT1B receptor, and 5-HT1D receptor.

Molecular Weight

403.48

Molecular Formula

C₂₃H₂₅N₅O₂

Targets

5-HT1B receptor: 9.4 (pKi); 5-HT1D receptor: 9.3 (pKi)

Form

Lyophilized powder

Purity

>98%

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

Donitriptan can be used to research and develop therapeutic strategies for certain diseases that involve excessive activation of GPCR-G protein signaling pathways.

Storage

Store at -20°C, and keep desiccated.