Properties
Description
Sitagliptin phosphate monohydrate, soluble in DMSO and water and insoluble in ethanol, prolongs the action of incretin hormones, thereby improving blood glucose control. It targets DPP-4.
Molecular Formula
C16H15F6N5O.H3PO4.H2O
Solubility
DMSO: 85 mg/mL (162.42 mM); Water: 35 mg/mL (66.88 mM); Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
Sitagliptin phosphate monohydrate is used in research to inhibit DPP-4, an enzyme involved in glucose metabolism, making it a target for type 2 diabetes studies.