Properties
Description
Teneligliptin hydrobromide, soluble in DMSO, water and ethanol, prolongs the action of incretin hormones, thereby improving blood glucose control. It targets Dipeptidyl peptidase-4, DPP-8, DPP-9, and FAP.
Molecular Formula
C44H65Br5N12O2S2
Targets
Dipeptidyl peptidase-4: 1.75 nM; DPP-8: 189 nM; DPP-9: 150 nM; FAP: >10 μM
Solubility
DMSO: 85 mg/mL (135.16 mM); Water: 85 mg/mL (135.16 mM); Ethanol: 14 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
Teneligliptin hydrobromide is employed in research to understand glucose metabolism and diabetic therapy by inhibiting the enzyme DPP-4, which effectively increases insulin secretion.
