The mechanical, structural, and biological properties of polysaccharide-based biomaterials determine their potential application in biomedicine. CD BioGlyco is committed to providing differential scanning calorimetry (DSC) analysis to help clients obtain characterization data relevant to thermal analysis, providing important information for further understanding of the properties and functions of Carbohydrate-based Biodegradable Materials.

DSC Analysis

Thermal analysis methods such as DSC, thermogravimetry (TGA), and dynamic mechanical thermal analysis (DMTA) have become powerful thermal analytical techniques for monitoring physical and chemical changes in natural and synthetic polymers. DSC is one of the most widely used thermal analytical techniques and plays a significant role in the field of materials analysis due to its fast, simple, and reliable measurement. DSC technology measures the change of enthalpy (endothermic, exothermic) or specific heat capacity of materials due to physical changes (phase change, melting, crystallization) or chemical reactions (oxidation, decomposition, dehydration) under the condition of linear temperature rise or constant temperature, thus inferring the physical structure and chemical changes of polysaccharide-based biomaterials.

Fig.1 DSC for cellulose acetate film (FAC) and cellulose acetate/biochar film (FAC-B). (Pinto, et al., 2019)

DSC Analysis of Polysaccharide-based Biodegradable Materials at CD BioGlyco

CD BioGlyco focuses on providing clients with professional and comprehensive services in the Characterization of Polysaccharide-based Biodegradable Materials. We offer two measurement methods for DSC analysis including heat flux and power compensation to help clients measure a wide range of thermodynamic and kinetic parameters such as specific heat capacity, enthalpy of reaction, latent energy, phase diagram, reaction rate, crystallization rate, the crystallinity of polymers, sample purity, etc. Our services include but are not limited to:

• Characterization of thermal phase transitions and measurement of heat of fusion and heat of crystallization
• Determination of the degree of purity in materials
• Determination of specific heat capacity of pure compounds or mixtures
• Determination of oxidative stability and thermal degradation in materials
• Determination of phase separation of polymer blend, copolymers
• Assessment of thermal stability of materials
• Determination of composition variations
• Kinetic analysis of chemical reaction or decomposition

Our DSC analysis services can be used to characterize multiple polysaccharide-based biodegradable materials, such as:

• Chitosan-based networks, such as cross-linked chitosan and chitosan/PEO blend.
• Chitosan-based films
• Starch-based materials
• Hyaluronic acid-based hydrogels

Example of DSC Analysis

DSC analysis is used to measure the change in enthalpy with chitosan-based film formulations. These measurements are critical for the manufacturing process of biomaterials and can be used to confirm the integrity of the chemical structure of chitosan during processing. The data obtained from the thermal analysis helps to enhance the applications of chitosan as a film former for medical use.

Advantages of Our DSC Analysis

• The simple and fast detection process
• Available in a wide temperature range (-90 to 550 °C)
• A small number of samples are required
• High-cost performance
• Sensitive recognition of even a slightly weak phase transition

Applications

• Quality control
• Polymer testing
• Crystallinity testing

Materials scientists and chemists at CD BioGlyco specialize in custom and innovative analyses to address your challenges in the Physical Characterization of Polysaccharide-based Biodegradable Materials. Our expert DSC analysis allows for a wealth of expertise in the field of thermal analysis for you.

If you are interested in our DSC analysis, please feel free to contact us for more details.