Properties
Description
GNE-6776, soluble in DMSO and ethanol and insoluble in water, targets and inhibits deubiquitinating enzymes, which play a crucial role in regulating protein degradation and maintaining cellular protein homeostasis.
Molecular Formula
C20H20N4O2
Solubility
DMSO: 67 mg/mL (192.3 mM); Water: Insoluble; Ethanol: 2 mg/mL (5.74 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
GNE-6776 focuses on DUB inhibition, which is important for understanding the regulation of protein turnover.