Properties
Description
IU1-47 targets and inhibits deubiquitinating enzymes, which play a crucial role in regulating protein degradation and maintaining cellular protein homeostasis. It targets UCH-L1, UCH-L1, and UCH-L3.
Molecular Formula
C19H23ClN2O
Targets
UCH-L1: 0.4 μM (Ki); UCH-L1: 0.88 μM; UCH-L3: 25 μM
Identity
Confirmed by NMR/HPLC/MS.
Applications
IU1-47 is a DUB inhibitor, similar to IU1, used in research to elucidate the functions of USP14 in protein degradation pathways.