Properties
Description
IU1, soluble in DMSO and ethanol and insoluble in water, targets and inhibits deubiquitinating enzymes, which play a crucial role in regulating protein degradation and maintaining cellular protein homeostasis. It targets USP14.
Molecular Formula
C18H21FN2O
Solubility
DMSO: 51 mg/mL (169.79 mM); Water: Insoluble; Ethanol: 51 mg/mL (169.79 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
IU1 is a DUB inhibitor that targets the USP14 enzyme, making it useful for understanding its regulatory role in protein homeostasis.
