Properties
Description
LDN-57444, soluble in DMSO and insoluble in ethanol and water, targets and inhibits deubiquitinating enzymes, which play a crucial role in regulating protein degradation and maintaining cellular protein homeostasis.
Molecular Formula
C17H11Cl3N2O3
Solubility
DMSO: 11 mg/mL (27.66 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
LDN-57444 is a DUB inhibitor applied in studies focusing on inhibiting ubiquitin C-terminal hydrolase L1 (UCHL1) and its potential in neurodegenerative diseases.
