DYRK inhibitor Paprotrain, Purity ≥98%

Synonym: 57046-73-8; Paprotrain; CHEMBL3753955; (Z)-2-(1H-indol-3-yl)-3-pyridin-3-ylprop-2-enenitrile; MKLP-2 Inhibitor; DYRK inhibitor

CAS Number: 57046-73-8
Compound CID: 12248889

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Paprotrain is designed to block the activity of dual-specificity tyrosine-regulated kinase (DYRK), which are involved in various cellular processes including cell differentiation and survival. It targets MKLP-2.

Molecular Weight

245.28

Molecular Formula

C₁₆H₁₁N₃

Targets

MKLP-2: 1.35 μM

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Applications

Paprotrain can be used to inhibit the mitotic kinesin Eg5, studied in cancer research.