DYRK inhibitor Paprotrain, Purity ≥98%

Synonym: 57046-73-8; Paprotrain; CHEMBL3753955; (Z)-2-(1H-indol-3-yl)-3-pyridin-3-ylprop-2-enenitrile; MKLP-2 Inhibitor; DYRK inhibitor

CAS Number: 57046-73-8
Compound CID: 12248889

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Paprotrain is designed to block the activity of dual-specificity tyrosine-regulated kinase (DYRK), which are involved in various cellular processes including cell differentiation and survival. It targets MKLP-2.

Molecular Weight

245.28

Molecular Formula

C₁₆H₁₁N₃

Targets

MKLP-2: 1.35 μM

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

Paprotrain can be used to inhibit the mitotic kinesin Eg5, studied in cancer research.

Storage

Store at -20ºC.