Properties
Description
COH000, soluble in DMSO and ethanol and insoluble in water, is a compound designed to target and inhibit the initial step of the ubiquitin-proteasome pathway.
Molecular Formula
C25H25NO5
Solubility
DMSO: 47 mg/mL (112.04 mM); Water: Insoluble; Ethanol: 1 mg/mL (2.38 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
COH000 is studied as an E1 activating inhibitor to uncover details of ubiquitin activation processes.
