Properties
Description
PYR-41, soluble in DMSO and insoluble in ethanol and water, is a compound designed to target and inhibit the initial step of the ubiquitin-proteasome pathway. It targets ubiquitin-activating Enzyme E1.
Molecular Formula
C17H13N3O7
Targets
Ubiquitin-activating enzyme E1: <10 μM
Solubility
DMSO: 72 mg/mL (193.9 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
PYR-41 is an E1 activating inhibitor used to examine its effects on ubiquitin-activating enzyme activity, influencing protein turnover research.