Properties
Description
NSC697923, soluble in DMSO and insoluble in ethanol and water, targets the E2 enzymes involved in the ubiquitin-proteasome pathway, aiming to modulate protein degradation processes that are critical for various cellular functions and implicated in numerous diseases. It targets E2 complex Ubc13-Uev1A.
Molecular Formula
C11H9NO5S
Targets
E2 complex Ubc13-Uev1A
Solubility
DMSO: 51 mg/mL (190.82 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
NSC697923 is an E2 conjugating inhibitor used to examine its impact on the ubiquitin-conjugating enzyme Ubc13, relevant in inflammation studies.