Properties
Description
Avadomide, soluble in DMSO and ethanol and insoluble in water, modulates the activity of E3 ubiquitin ligases, which play a critical role in targeting specific proteins for ubiquitination and subsequent degradation by the proteasome.
Molecular Formula
C14H14N4O3
Solubility
DMSO: 50 mg/mL (174.64 mM); Water: Insoluble; Ethanol: <1 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
Avadomide is studied as an E3 ligase inhibitor, which can modulate protein degradation pathways.
