Properties
Description
AG-1517, soluble in DMSO and insoluble in ethanol and water, is a compound that blocks the activity of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), both of which are involved in driving the growth and proliferation of certain types of cancer cells. It targets EGFR and EGFR.
Molecular Formula
C16H14BrN3O2
Targets
EGFR: 6 pM (Ki); EGFR: 25 pM
Solubility
DMSO: 6 mg/mL (16.65 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
AG-1517 is utilized for research on its EGFR tyrosine kinase inhibition and potential anti-cancer activities.
