Properties
Description
AG-494, soluble in DMSO and ethanol and insoluble in water, is a compound that blocks the activity of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), both of which are involved in driving the growth and proliferation of certain types of cancer cells. It targets EGFR.
Molecular Formula
C16H12N2O3
Solubility
DMSO: 50 mg/mL (178.39 mM); Water: Insoluble; Ethanol: 4 mg/mL (14.27 mM)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
AG-494 can be used to study the inhibition of EGFR tyrosine kinase in cellular signaling pathways.
