EGFR-HER2 inhibitor AG 555, Purity ≥98%

Synonym: 133550-34-2; AG555; AG 555; AG-555; Tyrphostin AG 555; EGFR-HER2 inhibitor

CAS Number: 133550-34-2
Compound CID: 5328770

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

AG 555, soluble in DMSO and ethanol and insoluble in water, is a compound that blocks the activity of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), both of which are involved in driving the growth and proliferation of certain types of cancer cells.

Molecular Weight

322.364

Molecular Formula

C₁₉H₁₈N₂O₃

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 63 mg/mL (195.43 mM); Water: Insoluble; Ethanol: 63 mg/mL

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

AG 555 can be used to study its effects on inhibiting the EGFR pathway in cancer cells.

Storage

Store at -20ºC.