EGFR-HER2 inhibitor AG 555, Purity ≥98%

Synonym: 133550-34-2; AG555; AG 555; AG-555; Tyrphostin AG 555; EGFR-HER2 inhibitor

CAS Number: 133550-34-2
Compound CID: 5328770

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

AG 555, soluble in DMSO and ethanol and insoluble in water, is a compound that blocks the activity of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), both of which are involved in driving the growth and proliferation of certain types of cancer cells.

Molecular Weight

322.364

Molecular Formula

C₁₉H₁₈N₂O₃

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 63 mg/mL (195.43 mM); Water: Insoluble; Ethanol: 63 mg/mL

Identity

Confirmed by NMR/HPLC/MS.

Applications

AG 555 can be used to study its effects on inhibiting the EGFR pathway in cancer cells.