EGFR-HER2 inhibitor Arry-380 analog, Purity ≥98%

Synonym: Arry-380; 937265-83-3; Arry380; HER2-Inhibitor-1; 6-[5-[[[2-(Methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]-4-quinazolinamine; 6-[5-[(2-Methylsulfonylethylamino)methyl]furan-2-yl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine; EGFR-HER2 inhibitor

CAS Number: 937265-83-3
Compound CID: 42598643

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Arry-380 analog, soluble in DMSO and ethanol and insoluble in water, is a potent and specific inhibitor of the tyrosine kinase activity of EGFR.

Molecular Weight

569.9

Molecular Formula

C₂₉H₂₇N₇O₄S

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 90 mg/mL (158 mM); Water: Insoluble; Ethanol: 3 mg/mL (5.26 mM)

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

Arry-380 analog can be used to study the inhibition of HER2 signaling in cancer research.

Storage

Store at -20ºC.