Properties
Description
ARRY-380, soluble in DMSO and ethanol and insoluble in water, is a compound that blocks the activity of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), both of which are involved in driving the growth and proliferation of certain types of cancer cells. It targets HER2.
Molecular Formula
C26H24N8O2
Solubility
DMSO: 87 mg/mL (181.05 mM); Water: Insoluble; Ethanol: 14 mg/mL (29.13 mM)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
ARRY-380 can be used to study its effects as a selective HER2 inhibitor in cancer therapy.
