Properties
Description
Avitinib, soluble in DMSO and ethanol and insoluble in water, is a compound that blocks the activity of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), both of which are involved in driving the growth and proliferation of certain types of cancer cells.
Molecular Formula
C26H26FN7O2
Solubility
DMSO: 90 mg/mL (184.6 mM); Water: Insoluble; Ethanol: 90 mg/mL (184.6 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
Avitinib can be used to investigate its efficacy as an irreversible EGFR inhibitor in EGFR-mutated cancers.
