Properties
Description
Avitinib, soluble in DMSO and ethanol and insoluble in water, is a compound that blocks the activity of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), both of which are involved in driving the growth and proliferation of certain types of cancer cells.
Molecular Formula
C26H26FN7O2
Solubility
DMSO: 90 mg/mL (184.6 mM); Water: Insoluble; Ethanol: 90 mg/mL (184.6 mM)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Avitinib can be used to investigate its efficacy as an irreversible EGFR inhibitor in EGFR-mutated cancers.
