EGFR-HER2 inhibitor Canertinib, Purity ≥98%

Synonym: Canertinib; 267243-28-7; CI-1033; PD-183805; Canertinib free base; N-(4-(3-Chloro-4-fluorophenylamino)-7-(3-morpholinopropoxy)quinazolin-6-yl)acrylamide; N-{4-[(3-Chloro-4-fluorophenyl)amino]-7-[3-(morpholin-4-yl)propoxy]quinazolin-6-yl}prop-2-enamide; EGFR-HER2 inhibitor

CAS Number: 267243-28-7
Compound CID: 156414

Product Size

10 mg; 25 mg; 50 mg; 100 mg; 200 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Canertinib, soluble in DMSO and ethanol and insoluble in water, is a potent and specific inhibitor of the tyrosine kinase activity of EGFR. It targets EGFR and ErbB2.

Molecular Weight

485.9

Molecular Formula

C₂₄H₂₅ClFN₅O₃

Targets

EGFR: 1.5 nM; ErbB2: 9.0 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 2 mg/mL (4.11 mM); Water: Insoluble; Ethanol: 8 mg/mL (16.46 mM)

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

Canertinib is employed to investigate its inhibitory effects on EGFR family kinases in cancer studies.

Storage

Store at -20ºC.