Properties
Description
CL-387785, soluble in warmed DMSO and insoluble in water and ethanol, is a compound that blocks the activity of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), both of which are involved in driving the growth and proliferation of certain types of cancer cells. It targets EGFR.
Molecular Formula
C18H13BrN4O
Solubility
Warmed DMSO: 61 mg/mL (160 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
CL-387785 is used to understand its irreversible inhibition of EGFR and its impacts on cancer cell growth.
