Properties
Description
CNX-2006, soluble in DMSO and ethanol and insoluble in water, is a compound that blocks the activity of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), both of which are involved in driving the growth and proliferation of certain types of cancer cells. It targets EGFR(L858R/T790M).
Molecular Formula
C26H27F4N7O2
Targets
EGFR(L858R/T790M): 20 nM
Solubility
DMSO: 90 mg/mL (164.97 mM); Water: Insoluble; Ethanol: 26 mg/mL (47.65 mM)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
CNX-2006 is applied to research its selective inhibition of EGFR mutants, contributing to studies on targeted cancer therapies.
