EGFR-HER2 inhibitor CNX-2006, Purity ≥98%

Synonym: 1375465-09-0; CNX2006; CNX 2006; EGFR-HER2 inhibitor

CAS Number: 1375465-09-0
Compound CID: 56968072

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

CNX-2006, soluble in DMSO and ethanol and insoluble in water, is a compound that blocks the activity of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), both of which are involved in driving the growth and proliferation of certain types of cancer cells. It targets EGFR(L858R/T790M).

Molecular Weight

545.53

Molecular Formula

C₂₆H₂₇F₄N₇O₂

Targets

EGFR(L858R/T790M): 20 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 90 mg/mL (164.97 mM); Water: Insoluble; Ethanol: 26 mg/mL (47.65 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

CNX-2006 is applied to research its selective inhibition of EGFR mutants, contributing to studies on targeted cancer therapies.