Properties
Description
DBPR112 is a compound that blocks the activity of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), both of which are involved in driving the growth and proliferation of certain types of cancer cells. It targets EGFR (L858R)/T790M and EGFRWT.
Molecular Formula
C32H31N5O3
Targets
EGFR (L858R)/T790M: 48 nM; EGFRWT: 15 nM
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
DBPR112 can be used to investigate its role as an EGFR tyrosine kinase inhibitor in cancer studies.
