Properties
Description
DBPR112 is a compound that blocks the activity of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), both of which are involved in driving the growth and proliferation of certain types of cancer cells. It targets EGFR (L858R)/T790M and EGFRWT.
Molecular Formula
C32H31N5O3
Targets
EGFR (L858R)/T790M: 48 nM; EGFRWT: 15 nM
Identity
Confirmed by NMR/HPLC/MS.
Applications
DBPR112 can be used to investigate its role as an EGFR tyrosine kinase inhibitor in cancer studies.
