EGFR-HER2 inhibitor DBPR112, Purity ≥98%

Synonym: 1226549-49-0; DBPR 112; DBPR-112; EGFR-HER2 inhibitor

CAS Number: 1226549-49-0
Compound CID: 46212971

Product Size

5 mg; 10 mg; 50 mg

Price

Datasheet

MSDS

Properties

Description

DBPR112 is a compound that blocks the activity of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), both of which are involved in driving the growth and proliferation of certain types of cancer cells. It targets EGFR (L858R)/T790M and EGFRWT.

Molecular Weight

533.62

Molecular Formula

C₃₂H₃₁N₅O₃

Targets

EGFR (L858R)/T790M: 48 nM; EGFRWT: 15 nM

Form

Lyophilized powder

Purity

Identity

Confirmed by NMR/HPLC/MS.

Applications

DBPR112 can be used to investigate its role as an EGFR tyrosine kinase inhibitor in cancer studies.