EGFR-HER2 inhibitor EAI045, Purity ≥98%

Synonym: 1942114-09-1; EAI-045; EAI 045; EGFR-HER2 inhibitor

CAS Number: 1942114-09-1
Compound CID: 121231412

Product Size

5 mg; 10 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

EAI045, soluble in DMSO and insoluble in ethanol and water, is a compound that blocks the activity of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), both of which are involved in driving the growth and proliferation of certain types of cancer cells. It targets EGFR mutants.

Molecular Weight

383.4

Molecular Formula

C₁₉H₁₄FN₃O₃S

Targets

EGFR mutants

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 75 mg/mL (195.61 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

EAI045 can be used to explore its role as an allosteric inhibitor of mutant EGFR in cancer treatment.