Properties
Description
EAI045, soluble in DMSO and insoluble in ethanol and water, is a compound that blocks the activity of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), both of which are involved in driving the growth and proliferation of certain types of cancer cells. It targets EGFR mutants.
Molecular Formula
C19H14FN3O3S
Solubility
DMSO: 75 mg/mL (195.61 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
EAI045 can be used to explore its role as an allosteric inhibitor of mutant EGFR in cancer treatment.
