EGFR-HER2 inhibitor EGFR-IN-7, Purity ≥98%

Synonym: 2267329-76-8; EGFR-IN-7; 5-Bromo-N4-[5-(dimethylphosphinyl)-6-quinoxalinyl]-N2-[2-methoxy-5-methyl-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-2,4-pyrimidinediamine; EGFR-HER2 inhibitor

CAS Number: 2267329-76-8
Compound CID: 138911391

Product Size

5 mg; 10 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

EGFR-IN-7, soluble in DMSO and insoluble in ethanol and water, is a compound that blocks the activity of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), both of which are involved in driving the growth and proliferation of certain types of cancer cells. It targets EGFR (C797S/T790M/L858R) and EGFR (WT).

Molecular Weight

694.6

Molecular Formula

C₃₂H₄₁BrN₉O₂P

Targets

EGFR (C797S/T790M/L858R): 0.218 nM; EGFR (WT): 7.92 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: Insoluble; Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

EGFR-IN-7 can be used to investigate its therapeutic potential as an EGFR inhibitor in oncology research.

Storage

Store at -20ºC.