EGFR-HER2 inhibitor Epertinib hydrochloride, Purity ≥98%

Synonym: 2071195-74-7; S-22611 hydrochloride; S22611; S 22611; EGFR-HER2 inhibitor

CAS Number: 2071195-74-7
Compound CID: 139290994

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Epertinib hydrochloride, soluble in DMSO and insoluble in ethanol and water, is a compound that blocks the activity of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), both of which are involved in driving the growth and proliferation of certain types of cancer cells. It targets EGFR, HER2 and HER4.

Molecular Weight

596.48

Molecular Formula

C₃₀H₂₈Cl₂FN₅O₃

Targets

EGFR: 1.48 ± 0.0 nM; HER2: 7.15 ± 0.5 nM; HER4: 2.49 ± 0.1 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 88 mg/mL (147.53 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

Epertinib hydrochloride can be utilized to investigate its dual inhibitory roles on EGFR and HER2 in oncology research.