EGFR-HER2 inhibitor Epertinib, Purity ≥98%

Synonym: 908305-13-5; S-22611; S22611; S 22611; EGFR-HER2 inhibitor

CAS Number: 908305-13-5
Compound CID: 46701811

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Epertinib is a compound that blocks the activity of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), both of which are involved in driving the growth and proliferation of certain types of cancer cells. It targets EGFR, HER2, and HER4.

Molecular Weight

560.02

Molecular Formula

C₃₀H₂₇ClFN₅O₃

Targets

EGFR: 1.48 ± 0.0 nM; HER2: 7.15 ± 0.5 nM; HER4: 2.49 ± 0.1 nM

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Applications

Epertinib can be used in studies evaluating its effects as a dual inhibitor of EGFR and HER2 in cancer treatment.