EGFR-HER2 inhibitor Erlotinib HCl, Purity ≥98%

Synonym: Erlotinib hydrochloride; 183319-69-9; erlotinib HCl; Tarceva; N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine hydrochloride; EGFR-HER2 inhibitor

MDL: MFCD07781272
CAS Number: 183319-69-9
Compound CID: 176871

Product Size

100 mg; 200 mg; 500 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Erlotinib HCl, soluble in warmed DMSO and insoluble in water and ethanol, is a potent and specific inhibitor of the tyrosine kinase activity of EGFR. It targets HER1/EGFR.

Molecular Weight

429.9

Molecular Formula

C₂₂H₂₃N₃O₄.HCl

Targets

HER1/EGFR: 2 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

Warmed DMSO: 4 mg/mL (9.3 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

Erlotinib HCl is used to study EGFR inhibition in non-small cell lung cancer research.

Storage

Store at -20ºC.