EGFR-HER2 inhibitor Erlotinib, Purity ≥98%

Synonym: Erlotinib; 183321-74-6; N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine; Tarceva; Erlotinib free base; 4-[(3-Ethynylphenyl)amino]-6,7-bis(2-methoxyethoxy)quinazoline; EGFR-HER2 inhibitor

MDL: MFCD02089651
CAS Number: 183321-74-6
Compound CID: 176870

Product Size

5 g; 10 g; 20 g

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Erlotinib, soluble in DMSO and warmed ethanol and insoluble in water, is a potent and specific inhibitor of the tyrosine kinase activity of EGFR. It targets EGFR.

Molecular Weight

393.443

Molecular Formula

C₂₂H₂₃N₃O₄

Targets

EGFR: 2 nM (IC₅₀, cell free assay)

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 68 mg/mL (172.83 mM); Water: Insoluble; Warmed ethanol: 13 mg/mL

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

Erlotinib can be used to study the inhibition of EGFR tyrosine kinase in cancer research.

Storage

Store at -20ºC.