EGFR-HER2 inhibitor Erlotinib, Purity ≥98%

Synonym: Erlotinib; 183321-74-6; N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine; Tarceva; Erlotinib free base; 4-[(3-Ethynylphenyl)amino]-6,7-bis(2-methoxyethoxy)quinazoline; EGFR-HER2 inhibitor

MDL: MFCD02089651
CAS Number: 183321-74-6
Compound CID: 176870

Product Size

5 g; 10 g; 20 g

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Erlotinib, soluble in DMSO and warmed ethanol and insoluble in water, is a potent and specific inhibitor of the tyrosine kinase activity of EGFR. It targets EGFR.

Molecular Weight

393.443

Molecular Formula

C₂₂H₂₃N₃O₄

Targets

EGFR: 2 nM (IC₅₀, cell free assay)

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 68 mg/mL (172.83 mM); Water: Insoluble; Warmed ethanol: 13 mg/mL

Identity

Confirmed by NMR/HPLC/MS.

Applications

Erlotinib can be used to study the inhibition of EGFR tyrosine kinase in cancer research.